The future of the human genome
Next Big Science article The next big challenge in genetic engineering is to design a way to sequence the entire genome without the need for a gene drive, which is used to accelerate progress in sequencing.
This will mean the use of genetic tools to sequence a genome in sequence.
But the cost of doing so, in terms of computing power, could make the sequencing process prohibitively expensive, and that’s where the sequencing technology is headed.
According to a new report from the National Center for Science Education (NCSE), the cost for sequencing a genome of human origin at this point is just under $10 billion.
The National Center For Science Education, a nonprofit organization based in Baltimore, Maryland, has recently released a new study on how the costs of sequencing a human genome will impact the future of genetic engineering.
The report looked at the cost associated with sequencing a single human genome from the human genomes of individuals with a total of 3.5 billion bases of DNA, or 1.6 billion DNA base pairs.
The new report found that this cost is currently around $1 billion per genome, or $10,000 per base.
In comparison, the cost to sequence an entire human genome is about $3 billion per base, or approximately $10 million per base (or $100 million per genome).
This is a dramatic change from the current sequencing cost, which currently is about one-tenth the cost.
“The future of genomic engineering will not be a technological revolution, but a fundamentally different type of science,” the report says.
“The fundamental science of genome sequencing will not change.
It will not move into a new phase of genetic sequencing, but will remain an essential part of the genetic engineering landscape.”
The report goes on to say that the cost per base is only going to increase with advances in the sequencing of RNA and protein.
“As the cost rises, the volume of RNA is expected to increase exponentially,” it says.
“If the cost increases by more than two orders of magnitude, the average cost per DNA base in sequencing is predicted to be $30,000, or more than three times the current cost of sequencing,” it adds.
“With the cost increasing, the amount of RNA sequenced per base will increase as well.”
According the NCSE, it is the potential cost of using sequencing to speed up genome sequencing that is the greatest barrier to this future.
The NCSE report finds that there are several barriers that prevent sequencing a DNA base, such as cost and availability of facilities and resources.
The report also says that the ability to use RNA sequencing to advance research in genetic medicine, a field of research that aims to create more efficient, safer and more effective treatments, is a barrier.
The study found that in addition to the cost, there are the logistics of sequencing, storage, packaging, distribution and other logistics, as well as the availability of data and other information needed to make accurate estimates of how many bases of RNA were sequenced.